Ellanse, created by AQTIS Medical BV, is a latex-free, pyrogen-free, and biodegradable temporary dermal filler. It consists of polycaprolactone (PCL) microspheres suspended in a gel carrier made of carboxymethylcellulose (CMC), glycerin, and phosphate-buffered saline. The range includes Ellanse S, M, L, and E, each designed to stimulate collagen production, resulting in firmer skin and reduced facial creases.

Ellanse is used to treat various areas, including the temples, brows, cheeks, nasolabial folds, jawlines, nose, marionette lines, and chin.

Collagen is essential for maintaining skin elasticity. In younger years, the body produces collagen abundantly, but aging and external factors can diminish its quantity and functionality. Ellanse utilizes PCL microspheres, which increase collagen synthesis and strengthen the skin scaffolding, filling and lifting skin depressions. This dermal filler offers tunable longevity and complete bioresorbability, ensuring long-lasting results and cost-effectiveness.

Only approved medical practitioners with experience in dermal injections should administer Ellanse. Adhering to aseptic guidelines is crucial to prevent infections and adverse effects. Patient's medical information should be thoroughly assessed for suitability, and they must be informed of the filler's warnings, precautions, aftercare methods, and potential effects.

Before treatment, disinfect the targeted areas, assess the need for pain relief, and administer appropriate anesthesia if required. Assemble the medical device following the provided patient information leaflet. Slowly inject the filler into the subdermal layer, using the tunneling technique if necessary. Massage the corrected areas for uniform gel distribution. Dispose of any remaining gel and used medical supplies according to guidelines.

Ellanse stands out from other fillers due to its remarkable longevity. The gel's viscoelastic properties allow it to last for an extended period before being completely absorbed into neighboring tissues. The effects of Ellanse can range from 1 to 4 years or more, depending on individual factors.

The Ellanse line of cosmetic fillers is extremely safe for injection into the human body, as it adheres to the highest European safety standards for Implantable Medical Devices. The ingredients used are non-toxic and tissue-friendly, causing no immunogenic or rejection reactions. Skin allergy tests are not required prior to the procedure, as these synthetic fillers do not contain any pyrogens or proteins. In fact, the fillers are CE-marked, which further verifies their superior quality. However, there are certain cases where caution is advised and the use of these fillers is not recommended due to an untested safety profile. These cases include patients with severe allergies or a history of anaphylactic shock, patients with allergies or hypersensitivity to any filler components, patients with dermal inflammation, infections, or disorders, patients prone to keloids or hypertrophic scarring, patients on cortisone therapy that may suppress connective tissue fiber growth, patients taking medications or supplements that promote bleeding, and patients with permanent implants in the treatment areas. Pregnant and breastfeeding patients, as well as individuals under 18 years of age, should also avoid using this filler due to the lack of established safety data. For a comprehensive list of contraindications, refer to the patient information leaflet.

As with any minimally invasive injection procedure, patients may experience localized inflammatory reactions as common side effects, including swelling, bruising, and redness. These effects are typically mild and resolve within a couple of days. Patients should avoid high-impact exercise for at least one day following the treatment and protect the treated areas from excessive sunlight exposure for a week post-procedure. Rare side effects may include induration (hardening of tissues), infection, and allergic reactions. These reactions are severe and require urgent medical attention. For a detailed list of side effects, consult the patient information leaflet.

Ellanse fillers are composed of polycaprolactone (PCL) microspheres uniformly suspended in a gel carrier consisting of carboxymethylcellulose (CMC), glycerin, and phosphate-buffered saline. This synthetic gel is free from latex and pyrogens and can be fully absorbed by the surrounding tissues. Known as collagen stimulators, Ellanse fillers encourage the skin to produce more collagen. Over time, this leads to lifted, tighter, and smoother-looking skin.