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EUFLEXXA is a sterile solution with viscoelastic properties of highly purified sodium hyaluronate with high molecular weight in phosphate buffered saline. Sodium hyaluronate is a physiological substance found in animal and human tissues. EUFLEXXA is a very highly purified medical device obtained from bacterial cells. It is a polysaccharide consisting of repeating disaccharides of N-acetylglucosamine sodium glucuronate, connected by alternating bonds. Hyaluronan is found in the synovial fluid, in the vitreous and aqueous humor of the eye, in the skin and the umbilical cord.
INDICATIONSEUFLEXXA is intended for the relief of pain caused by knee osteoarthritis. EUFLEXXA helps in pairing the joint, allows greater mobility and flexibility of the treated joint, and reduces pain in the affected knee.
CONTRAINDICATIONSEUFLEXXA should not be used in patients with known hypersensitivity to hyaluronan-containing preparations and patients with knee infection, infection or skin disease at the injection site.
DOSAGEEach syringe is for single use only. The syringe should be opened immediately after opening the individual packaging. Usually 2 ml is injected into the affected joint once a week for three consecutive weeks.
SIDE EFFECTSIn clinical trials, a total of 160 patients were given 478 injections. 18 patients had 31 adverse reactions that could be associated with a medical device. The most common events were joint pain. Of these, there were only two serious events.
ADDITIONAL INFORMATIONStore in a dark and cool place (temp. 2-8 degrees C). Do not freeze. Can be removed from the refrigerator and stored at room temperature (15-25 degrees C) for no more than 6 months within the shelf life.
INGREDIENThyaluronic acid 
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